In all children, effective plasma concentrations of itraconazole were reached within 3 to 5 days after initiation of treatment and maintained throughout treatment.
Opportunistic hyaline moulds: Hearing loss Transient or permanent hearing loss has been reported in patients receiving treatment with itraconazole.
Itraconazole oral solution should not be used in patients with congestive heart failure or with a history of congestive heart failure unless the benefit clearly outweighs the risk. Prescription only medicine.
Sorbitol E420 190 microlitre per ml , ethanol. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.
Since clinical data on the use of itraconazole in paediatric patients is limited, its use in children is not recommended unless the potential benefit outweighs the potential risks see section 4.
In these patients treatment should be stopped immediately and liver function testing should be conducted. If signs or symptoms of congestive heart failure occur during administration of Itraconazole Oral Solution, continued Itraconazole Oral Solution use should be reassessed. Company contact details Beacon Pharmaceuticals.
Itraconazole oral solution is indicated for use in adults. The intermediate category is sometimes called Susceptible-Dose Dependent SDD and both categories are equivalent for itraconazole.
In vitro studies have shown that CYP3A4 is the major enzyme involved in the metabolism of itraconazole. Azole antifungals.
Renal Insufficiency Limited data are available on the use of oral itraconazole in patients with renal impairment.
Paracoccidioides brasiliensis 1. After oral intake, itraconazole is rapidly taken up by the organism.
Itraconazole Oral Solution. Such patients should be informed of the signs and symptoms of CHF, should be treated with caution, and should be monitored for signs and symptoms of CHF during treatment.