Folate deficiency can occur in diets that supply insufficient amounts of these foods.
Talk to your doctor if you see any signs of anemia so you and your doctor can come up with a treatment plan and help prevent any permanent damage. The Merck Manual-Home Edition. One test used to diagnose many forms of anemia is the complete blood count CBC.
Common symptoms include:. Mayo Clinic for Medical Education and Research.
Years Published 1987, 1989, 2003, 2008. Vitamin B is a key player in maintaining cell health and keeping you energized.
In microcytic anemia, the cells are smaller than normal. Much rarer causes of megaloblastic anemia unrelated to vitamin deficiency have been identified including rare enzyme deficiencies known as inborn errors of metabolism and primary bone marrow disorders including myelodysplastic syndromes and acute myeloid leukemia.
Box 30105 Bethesda, MD 20892-0105 Phone: Folate, which is also known as folic acid, is a B vitamin that is normally found in green leafy vegetables, citrus fruits, and certain grains and nuts. Folate deficiency may also result from conditions which use up or require excessive amounts of folate.
It can occur in individuals of any racial or ethnic background. Management, prevention and control of megaloblastic anemia, secondary to folic acid deficiency.
General Discussion Megaloblastic anemia is a condition in which the bone marrow produces unusually large, structurally abnormal, immature red blood cells megaloblasts. People who have pernicious anemia also may be at higher risk for weakened bone strength and stomach cancer. Because the cells are too large, they may not be able to exit the bone marrow to enter the bloodstream and deliver oxygen.
The most common cause of microcytic anemia is iron-deficiency anemia, usually due to poor dietary intake or blood loss, such as menstrual blood loss or through the gastrointestinal tract.
A diagnosis of megaloblastic anemia is made based upon a thorough clinical evaluation, a detailed patient history, identification of characteristic findings and a variety of blood tests.
Supplementation of either cobalamin or folate may also be required. It helps make DNA and produce red blood cells.
These two nutrients are necessary for producing healthy red blood cells. Investigational Therapies Information on current clinical trials is posted on the Internet at www. Preventive prophylactic folate supplementation may be recommended for individuals who have higher-than-normal demands for folate such as pregnant women.